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Since skeletal muscle appears to play some role in controlling the flux of ammonia in the body, muscle mass depletion may lead to worsening of HE, although this effect has not been consistently demonstrated

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Neurology Parkinson’s disease (PD) is the second most common neurodegenerative disorder in the elderly population and besides severe motor symptoms it is also associated with GI motility abnormalities [99,170], which may include small intestine dysbiosis as a result of delayed OCTT